Brain metastases are the most common intracranial tumors in adults, accounting for significantly more than 50% of brain tumors. About 30~40% of all cancer patients is known to develop brain metastases. There has been an increase in metastatic brain lesions due to better early detection, as well as better treatments for primary cancer leading to longer patient survival.

Primary brain tumors are tumors that originate from the tissues of the brain or the brain's immediate surroundings. Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor in adults. Glioblastoma accounts for over 60% of all primary brain and CNS tumors. Only 10% of patients survive 5 years following diagnosis.

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Alzheimer’s disease is a common neurodegenerative disease that destroys memory, thinking and behavior. Today there are 50 million AD patients worldwide, and its incidence doubles every 5 years after the age of 60 year.

Parkinson’s disease is most common neurodegenerative disorder that affects nerve cells in the brain responsible for body movement. An estimated 10 million people worldwide have Parkinson's disease.