Pipelines
| Product | Modality | Indication | Target | Lead | Candidate | Preclin. | Phase I | Partner | Grant |
| AMB302 | ADC | GBM, bladder | FGFR3 |  |
 |
||||
| AMB001 | mAb | Atopic dermatitis & dementia |
CD200R1 | |
|||||
| AMB018 | BsAb | Solid tumors | |
||||||
| AMB501 | CAR-NK | Solid tumors |  |
||||||
| AMB015 | ADC | Hematologic & solid tumors |
Undisclosed | ||||||
| AMB020 | Small molecule |
GBM | Undisclosed | ||||||
| AMB011 | BsAb | CNS |
Platforms
| Product | Tech | Indication | Class | PoC | L/O | Partner | Grant |
| AMB401 | Payload | Solid tumors | Duocarmycin | Undisclosed | |||
| AMB402 | Payload | Solid tumors | |||||
| AMB008 | BBB penetration |
Brain diseases |
| Product | Modality | Development Status |
|---|---|---|
| AMB302 | ADC | Pre-Clinical |
| Indication | ||
| Bladder cancer, GBM, solid tumors | ||
Partner
Grant
An FGFR3 targeting ADC program that utilizes AIMEDBIO’s proprietary antibody to target FGFR3 overexpressing solid tumors and glioblastomas with FGFR3-TACC3 fusion.
| Product | Modality | Development Status |
|---|---|---|
| AMB001 | mAb | Pre-Clinical |
| Indication | ||
| Atopic dermatitis, dementia | ||
Grant
An anti-CD200R1 monoclonal antibody which regulates immune checkpoint through agonistic effect.
| Product | Modality | Development Status |
|---|---|---|
| AMB018 | BsAb | Candidate selection |
| Indication | ||
| Solid tumor | ||
Grant
| Product | Modality | Development Status |
|---|---|---|
| AMB501 | CAR-NK | Candidate selection |
| Indication | ||
| Solid tumor | ||
Partner
| Product | Modality | Development Status |
|---|---|---|
| AMB015 | ADC | Candidate selection |
| Indication | Partner | |
| Hematologic & solid tumor | Undisclosed | |
| Product | Modality | Development Status |
|---|---|---|
| AMB020 | Small molecule | Candidate selection |
| Indication | Partner | |
| GBM | Undisclosed | |
| Product | Modality | Development Status |
|---|---|---|
| AMB011 | BsAb | Candidate selection |
| Indication | ||
| CNS | ||
Platforms
| Product | Modality | Indication |
|---|---|---|
| AMB401 | Payload | PoC |
| Indication | Class | Partner |
| Solid tumors | Duocarmycin | Undisclosed |
| Product | Modality | Indication |
|---|---|---|
| AMB402 | Payload | PoC |
| Indication | ||
| Solid tumors |
| Product | Modality | Indication |
|---|---|---|
| AMB008 | BBB penetration | PoC |
| Indication | ||
| Solid tumors |
